The Wealth Index is based on a number of indicators of affluence including average household income and average net worth, but it also includes the value of material possessions and resources. It represents the wealth of the area relative to the national level. Values above or below 100 represent above-average wealth or below-average wealth compared to the national level.
| Name | County | Wealth Index | |
|---|---|---|---|
| 1. | Osaka Census Designated Place | Wise | 22 |
| 2. | Allison Gap Census Designated Place | Smyth | 23 |
| 3. | Dante Census Designated Place | Russell | 23 |
| 4. | Falls Mills Census Designated Place | Tazewell | 23 |
| 5. | Big Rock Census Designated Place | Buchanan | 25 |
| 6. | Villa Heights Census Designated Place | Henry | 25 |
| 7. | Town of Dungannon | Scott | 27 |
| 8. | New Church Census Designated Place | Accomack | 28 |
| 9. | Town of Melfa | Accomack | 29 |
| 10. | Town of Pocahontas | Tazewell | 29 |
| 11. | Town of Pennington Gap | Lee | 30 |
| 12. | Riverview Census Designated Place | Wise | 30 |
| 13. | Doran Census Designated Place | Tazewell | 30 |
| 14. | Fieldale Census Designated Place | Henry | 30 |
| 15. | York Haven Anchorage | York | 30 |
| 16. | Willis Wharf Census Designated Place | Northampton | 31 |
| 17. | Town of Gretna | Pittsylvania | 31 |
| 18. | Town of Cleveland | Russell | 31 |
| 19. | Town of Jonesville | Lee | 31 |
| 20. | Rio Census Designated Place | Albemarle | 32 |